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2 Materials and methods 2.1 Experimental animals Male C57BL/6J mice [specific-pathogen-free (SPF) grade], aged 810 weeks and weighing 2025 g, were obtained from the Laboratory Animal Center of Ningxia Medical University

This work was supported by the Postdoctoral Fellowship Program of CPSF (GZC20251840), the National Natural Science Foundation of China (Grants 32370110 and 323B2004), the Gansu Province Major Science and Technology Project (Grant 24ZDWA005), and the Fundamental Research Funds for the Central Universities (Grant lzujbky-2025-jdzx05)

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